Oh yea, especially these newer 512MB video cards that are released today, now size is an issue for most MB's and their cases. These cards have HUGE fans and sinks that takes up two PCI slots. The bigger the memory size, the bigger the card becomes itself.

It's just something to be aware when you are upgrading components of your computer. Not everything is getting smaller in physical size...sometimes an item may get bigger to accomidate for the newer size/features.